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The grand-daughter of the famed Hollywood screenwriter Edwin Justus Mayer (To Be Or Not To Be, Midnight and Desire), Daisy von Scherler Mayer grew up 'backstage' in New York City where her parents were actress, Sasha von Scherler, and writer, Paul Avila Mayer (creator of Ryan's Hope).

Working behind the scenes at the New York Shakespeare Festival as a teenager, Von Scherler Mayer went on to graduate with a degree in theatre and history from Wesleyan University. After college, she directed contemporary interpretations of classic plays such as Euripides Electra, Shakespeare's The Tempest and Two Gentleman in Verona.

Her feature film directing debut was the critically acclaimed 1995 hit Party Girl, which she also co-wrote with partner Harry Birckmayer. Party Girl starred Parker Posey and her mother. The success of Party Girl also led to a FOX television series.

Since then, Von Scherler Mayer has been busy writing and directing films. She directed Madeline, which was based on Ludwig Bemelman's classic children's books about the escapade little readhead French girl. The film starred Academy Award winner Frances McDorman, Nigel Hawthorne and Hatty Jones as Madeline. She currently lives in Brooklyn, New York with her husband.